George Goodwin is a Research Fellow at the Wolfson Sensory, Pain and Regeneration Centre. His research focuses on understanding the neurobiology of arthritis pain, with the goal of identifying new drug targets for more effective analgesic therapies. His lab uses a range of approaches, including in vivo calcium imaging, transgenic mouse lines, behavioural assays and histology, to study sensory neurons in mouse models of rheumatoid and osteoarthritis. The current focus of his research is to define the role of silent nociceptors - specialised sensory neurons that become activated following inflammation - in arthritis pain.
Publications
George L Goodwin, Glenn Franken
bioRxiv, Cold Spring Harbor Laboratory, 2025, pp. 2025--05
George L Goodwin, Alina-Cristina Marin, Julia Vlachaki Walker, Carl Hobbs, Franziska Denk
Arthritis Research \& Therapy, vol. 27, BioMed Central London, 2025, p. 67
Spontaneous activity in peripheral sensory nerves: a systematic review
Dongchan Choi, George Goodwin, Edward B Stevens, Nadia Soliman, Barbara Namer, Franziska Denk
Pain, vol. 165, LWW, 2024, pp. 983--996
Assessing spontaneous sensory neuron activity using in vivo calcium imaging
Sonia Ingram, Kim I Chisholm, Feng Wang, Yves De Koninck, Franziska Denk, George L Goodwin
Pain, vol. 165, LWW, 2024, pp. 1131--1141
In vivo calcium imaging shows that satellite glial cells have increased activity in painful states
Sara E Jager, George Goodwin, Kim I Chisholm, Franziska Denk
Brain Communications, vol. 6, Oxford University Press US, 2024, pp. fcae013
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